Here's something for you to mull over:
What if your favorite (movie/TV show/animated series/radio drama/video game/OVA/etc.) was remade into a different format, but did not reuse any of the original vocal cast - would you still watch it?
For example: Say Firefly/Serenity was made into a video game - a cooperative venture between Bethesda, BioWare, and Valve. It releases on PC and all consoles, has no DRM, and has pretty much everything every die-hard fan could want - except none of the original cast reprise their roles (e.g. Captain Malcolm Reynolds is voiced by Nolan North, etc. etc.).
In your answer, list your favorite show/movie/etc. and a little bit on why you would or wouldn't support it without the original cast.