I was at my Mom's place over the Holidays and got these. She spent the last part of her career with the Shuttle program and you're looking at a pile of mission patches from the first 35 missions. By far and away, the coolest one is front and center: the Enterprise patch from the approach/glide tests they did in prior to the first space shots.
Now I'm thinking about collecting the rest. I've got a pretty good start with arguably the oldest/rarest.